Al-Qadisiyah Journal For Agriculture Sciences

How Using Probiotics in Poultry Can Fight the Spread of Antibiotic Resistance to Humans?

Document Type : Review Paper

Authors

Shameeran Salman Ismael 1
Bland Husamuldeen Abdullah 2
Shaimaa Hamid Hasan 3
Amal Jamil Sadiq 2
Diyan Mosa Omer 2

1 Medical Laboratory Sciences Department, College of Health Sciences/ University of Duhok

2 Medical Laboratory Sciences Department, College of Health Sciences, University of Duhok, Iraq

3 Anesthesia Sciences Department, College of Health Sciences, University of Duhok, Iraq

https://doi.org/10.33794/qjas.2023.143760.1143
Abstract
Globally, there is a severe problem with antibiotic resistance in animals and humans. It may result in diseases that are extremely challenging to treat. In certain situations, conventional antibiotics used to treat an illness may no longer be effective in poultry and an alternative treatment is used. Therefore, using probiotics instead of antibiotic therapy to treat specific health issues in both humans and animals can achieve the desired result, such as preventing infectious zoonotic diseases and enhancing general health. Probiotics are friendly live microorganisms like normal flora, when consumed in a sufficient dose which produces positive effects on the host. This review aimed to prove that using probiotics in poultry instead of antibiotics can fight the spread of pathogenic bacteria such as Salmonella and Campylobacter to humans by ingestion of undercooked poultry meat infected with these bacteria and also increase antibiotic resistance to humans. Finally, concluded that probiotics play a potential role in the spread of antibiotic-resistance genes in our natural environments, we believe it is crucial to implement proper regulation on their use in both livestock and human applications globally.

Keywords

Antibiotic resistance
Probiotics
Poultry meat
infectious diseases
Subjects
  1. Al-Khalaifah, H.S. (2018). Benefits of probiotics and/or prebiotics for antibiotic-reduced poultry. Poultry Science. 97(11), 3807-3815. https://doi.org/10.3382/ps/pey160
  2. Gadde, U.D., Oh, S., Lillehoj, H.S., Lillehoj, E.P. (2018). Antibiotic growth promoters virginiamycin and bacitracin methylene disalicylate alter the chicken intestinal metabolome. Scientific Reports, 8(1), 1-8. https://doi.org/10.1038/s41598-018-22004-6
  3. Butaye, P., Devriese, L.A., Haesebrouck, F. (2003).Antimicrobial growth promoters used in animal feed: effects of less well known antibiotics on gram-positive bacteria. Clin. Microbiol. Rev., 16,175–88. https://doi.org/10.1128/CMR.16.2.175-188.2003
  4. Phillips, I., Casewell, M., Cox, T., De Groot ,B., Friis, C., et al. (2004).Does the use of antibiotics in food animals pose a risk to human health? A critical review of published data. The Journal of antimicrobial chemotherapy, 53(1).28–52. https://doi.org/10.1093/jac/dkg483
  5. van den Bogaard, A.E., Stobberingh, E.E. (2000). Epidemiology of resistance to antibiotics: links between animals and humans. Int. J. Antimicrob. Agents, 14,327–335. https://doi.org/10.1016/s0924-8579(00)00145-x
  6. O'neill, J.I.M. (2014).Antimicrobial resistance: tackling a crisis for the health and wealth of nations. Rev. Antimicrob. Resist.
  7. Prestinaci,, Pezzotti, P.,Pantosti, A. (2015). Antimicrobial resistance: a global multifaceted phenomenon, Pathogens and Global Health, 109(7), 309-318.https://doi.org/10.1179/2047773215Y.0000000030
  8. Castanon, J.I. (2007). History of the use of antibiotic as growth promoters in European poultry feeds. Poultry Science, 86(11), 2466–2471. https://doi.org/10.3382/ps.2007-00249
  9. Manges, A.R. (2016).Escherichia coli and urinary tract infections: the role of poultry-meat. Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 22(2), 122–129. https://doi.org/10.1016/j.cmi.2015.11.010
  10. van Rennings, L., von Münchhausen, C., Hartmann, M., Ottilie, H., Honscha, W., et al. (2014). Antibiotikaverbrauch und Antibiotikaverkauf in Deutschland im Jahr 2011--Zur Situation des Arzneimitteleinsatzes in der Veterinärmedizin [Antibiotic usage and antibiotic sales in Germany in 2011--the situation of drug usage in veterinary medicine]. Berliner und Munchener tierarztliche Wochenschrift, 127(9-10), 366–374
  11. EFSA Panel on Biological Hazards (BIOHAZ), (2012). EFSA Panel on Contaminants in the Food Chain (CONTAM) and EFSA Panel on Animal Health and Welfare (AHAW). Scientific Opinion on the public health hazards to be covered by inspection of meat (poultry). EFSA Journal, 10(6), 2741
  12. Spina, A., Kerr, K.G., Cormican, M.., Barbut, F., Eigentler, A., et al. (2015).Spectrum of enteropathogens detected by the FilmArray GI Panel in a multicentre study of community-acquired gastroenteritis. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 21(8), 719–728. https://doi.org/10.1016/j.cmi.2015.04.007
  13. Arora, M., Baldi, A. (2015). Regulatory categories of probiotics across the globe: A review representing existing and recommended caterorization. Indian J Med Microbiol, 33,S2–S10. https://doi.org/10.4103/0255-0857.150868
  14. Mehdi, Y., Létourneau-Montminy, M., Gaucher, M., Chorfi, Y., Suresh, G., et al. (2018). Use of antibiotics in broiler production: Global impacts and alternatives. Animal Nutrition, 4(2), 170-178. https://doi.org/10.1016/j.aninu.2018.03.002
  15. Alagawany M, Abd El-Hack ME, Farag MR, Sachan S, Karthik K, Dhama K. The use of probiotics as eco-friendly alternatives for antibiotics in poultry nutrition. Environ Sci Pollut Res. 2018; 25:10611–8. https://doi.org/10.1007/s11356-018-1687-x
  16. Sharma S, Galav V, Agrawal M, Faridi F, Kumar B. Multi-drug resistance pattern of bacterial flora obtained from necropsy samples of poultry. J Anim Health Prod. 2017; 5:165–71. http://dx.doi.org/10.17582/journal.jahp/2017/5.4.165.171
  17. Bajagai, Y.S., Klieve, A.V., Dart, P.J., Bryden, W.L. (2016). Animal production and health div probiotics In: Animal nutrition: production, impact and regulation.Rome, Italy: Food and Agriculture Organization of the United Nations.
  18. Angelakis, E. (2017).Weight gain by gut microbiota manipulation in productive animals. Microb Pathog, 106,162–70. https://doi.org/10.1016/j.micpath.2016.11.002
  19. Abd El-Moneim, A.E., Sabic, E.M. (2019). Beneficial effect of feeding olive pulp and Aspergillus awamori on productive performance, egg quality, serum/yolk cholesterol and oxidative status in laying Japanese quails. Journal of Animal and Feed Sciences, 28(1),52-61. https://doi.org/10.22358/jafs/105537/2019
  20. El-Moneim, A.E.E.A., El-Wardany, I., Abu-Taleb, A.M., Wakwak, M.M., Ebeid, T.A., Saleh, A.A. (2020. Assessment of In Ovo Administration of Bifidobacterium bifidum and Bifidobacterium longum on Performance, Ileal Histomorphometry, Blood Hematological, and Biochemical Parameters of Broilers. Probiotics Antimicrob Proteins, 12(2),439-450. https://doi.org/10.1007/s12602-019-09549-2
  21. Klose, V., Mohnl, M., Plail, R., Schatzmayr, G., Loibner, A.P. (2006) Development of a competitive exclusion product for poultry meeting the regulatory requirements for registration in the European Union. Mol Nutr Food Res., 50,563–7. https://doi.org/10.1002/mnfr.200500166
  22. Gadde, U.D., Kim, W.H., Oh, S.T., Lillehoj, H.S. (2017). Alternatives to antibiotics for maximizing growth performance and feed efficiency in poultry: a review. Anim Health Res Rev., 18,26–45. https://doi.org/10.1017/S1466252316000207
  23. Mountzouris, K., Tsirtsikos, P., Kalamara, E., Nitsch, S., Schatzmayr, G., Fegeros, K. (2007). Evaluation of the Efficacy of a Probiotic Containing Lactobacillus, Bifidobacterium, Enterococcus, and Pediococcus Strains in Promoting Broiler Performance and Modulating Cecal Microflora Composition and Metabolic Activities. Poultry Science, 86(2), 309-317. https://doi.org/10.1093/ps/86.2.309
  24. Cakιr, S., Midilli, M., Alp, M., Ylιmaz, H., Muglal, O.H., Turan, N., Kocabaglι, N. (2008). Effects of dietary probiotic and prebiotic supplementation on growth performance and serum IgG concentration of broilers. South African journal of animal science, 38(1), 21-27. https://hdl.handle.net/10520/EJC94558
  25. Awad, W.A., Ghareeb, K., Abdel-Raheem, S., Böhm, J. (2009). Effects of dietary inclusion of probiotic and synbiotic on growth performance, organ weights, and intestinal histomorphology of broiler chickens. Poultry science, 88(1), 49-56. https://doi.org/10.3382/ps.2008-00244
  26. Zhou, X., Wang, Y., Gu, Q., Li ,W. (2010). Effect of dietary probiotic, Bacillus coagulans, on growth performance, chemical composition, and meat quality of Guangxi Yellow chicken. Poultry science, 89(3), 588-593. https://doi.org/10.3382/ps.2009-00319
  27. Sohail, M.U., Rahman, Z.U., Ijaz, A., Yousaf, M.S., Ashraf, K., Yaqub, T., Rehman, H. (2011).Single or combined effects of mannan-oligosaccharides and probiotic supplements on the total oxidants, total antioxidants, enzymatic antioxidants, liver enzymes, and serum trace minerals in cyclic heat-stressed broilers. Poultry Science, 90(11), 2573-2577. https://doi.org/10.3382/ps.2011-01502
  28. Král, M,, Angelovičová, M., Mrázová, Ľ. (2012). Application of probiotics in poultry production. Animal Science and Biotechnologies, 45(1), 55-57.
  29. Tellez, G., Pixley, C., Wolfenden, R.E., Layton, S.L., Hargis, B.M. (2012). Probiotics/direct fed microbials for Salmonella control in poultry. Food Research International, 45(2), 628-633. http://dx.doi.org/10.1016/j.foodres.2011.03.047
  30. Taheri, H.R., Moravej, H. (2010)., Tabandeh F, Zaghari M, Shivazad M. Efficacy of combined or single use of Lactobacillus crispatus LT116 and L. johnsonii LT171 on broiler performance. British Poultry Sciences, 51(5), 580-585.
  31. Hume, M.E. (2011). Historic perspective: prebiotics, probiotics, and other alternatives to antibiotics. Poultry Science, 90(11), 2663-2669.
  32. Chegeni, A. (2012).The effect of a synbiotic-a cocktail of pre and probiotic-on broiler performance and litter quality. In Proceedings of the 23rd Annual Australian Poultry Science Symposium, Sydney, New South Wales, Australia, 298-301. Poultry Research Foundation.
  33. Patterson, J.A., Burkholder, K.M. (2003). Application of prebiotics and probiotics in poultry production. Poultry Science, 82(4), 627-631. https://doi.org/10.1093/ps/82.4.627
  34. Madej, J.P., Stefaniak, T., Bednarczyk, M. (2015). Effect of in ovo-delivered prebiotics and synbiotics on lymphoid-organs’morphology in chickens. Poultry Science, 94(6),1209-1219. https://doi.org/10.3382/ps/pev076
  35. Pruszynska-Oszmalek, E., Kolodziejski, P.A., Stadnicka, K., Sassek, M., Chalupka, D., Kuston, B., Bednarczyk, M. (2015). In ovo injection of prebiotics and synbiotics affects the digestive potency of the pancreas in growing chickens. Poultry Science, 94(8), 1909-1916. https://doi.org/10.3382/ps/pev162
  36. Varankovich, N.V., Nickerson, M.T., Korber, D.R. (2015). Probiotic-based strategies for therapeutic and prophylactic use against multiple gastrointestinal diseases. Frontiers in Microbiology, 6,685. https://doi.org/10.3389/fmicb.2015.00685
  37. Abd El-Hack, M.E., El-Saadony, M.T., Shafi, M.E., Qattan, S.Y., Batiha, G.E., et al. (2020). Probiotics in poultry feed: A comprehensive review. Journal of Animal Physiology and Animal Nutrition, 104(6),1835-1850. https://doi.org/10.1111/jpn.13454
Al-Qadisiyah Journal For Agriculture Sciences
Volume 13, Issue 2
December 2023
Page 105-109

  • Receive Date 05 October 2023
  • Accept Date 23 October 2023